Your High-Protein Diet Could Be Hardening Your Arteries

[Curt]

Leucine Exposed: How Your High-Protein Diet Could Be Hardening Your Arteries

https://scitechdaily.com/leucine-exposed-how-your-high-protein-diet-could-be-hardening-your-arteries/

By UNIVERSITY OF PITTSBURGH FEBRUARY 26, 2024 By UNIVERSITY OF PITTSBURGH FEBRUARY 26, 2024

High protein consumption may elevate atherosclerosis risk by activating immune cells that contribute to arterial plaque formation, with leucine playing a critical role.

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk. The findings were published on February 19 in Nature Metabolism.

The study, which combined small human trials with experiments in mice and cells in a Petri dish, showed that consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation, driving the disease risk. Furthermore, the scientists showed that one amino acid – leucine – seems to have a disproportionate role in driving the pathological pathways linked to atherosclerosis, or stiff, hardened arteries.

The Risks of High-Protein Diets
“Our study shows that dialing up your protein intake in pursuit of better metabolic health is not a panacea. You could be doing real damage to your arteries,” said senior and co-corresponding author Babak Razani, M.D., Ph.D., professor of cardiology at Pitt. “Our hope is that this research starts a conversation about ways of modifying diets in a precise manner that can influence body function at a molecular level and dampen disease risks.”

Interestingly, the analysis of circulating amino acids showed that leucine – an amino acid enriched in animal-derived foods like beef, eggs, and milk – is primarily responsible for abnormal macrophage activation and atherosclerosis risk, suggesting a potential avenue for further research on personalized diet modification, or “precision nutrition.”

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From another report:
But if you're still worried about protein, remember that leucine lives predominantly in animal proteins. That means if you want to continue to favor protein as your macro of interest, the best place to get it may be from plant sources.

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A summary podcast: https://scitechdaily.com/the-last-spark-consciousness-in-the-dying-brain-unveiled/

[rahab]

Thank you for sharing this report

[Curt]

God be praised. He is giving us the proofs we need for following His plan.

Follow the data
Follow the money

[rahab]

God be praised. He is giving us the proofs we need for following His plan.

Follow the data
Follow the money

“Thumbs up”

[Richard Myers]

Great information. I was worried until that last part. I was thinking the problem was not protein, but animal protein. As we age, we like the young need more protein from what I have read. We do not hear about protein deficiencies in countries where there is abundance of foods with protein.  Once again science has supported what we have been given over a hundred years ago. We ought to be eating a wide variety of foods given to us at the creation. But, not at one meal.