Author Topic: Sleep  (Read 44495 times)

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rahab

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Re: 284 - How The Brain Cleans Cellular Debris While We Sleep
« Reply #80 on: February 07, 2025, 01:14:50 PM »
 :)

rahab

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Re: 284 - How The Brain Cleans Cellular Debris While We Sleep
« Reply #81 on: February 08, 2025, 02:33:56 PM »
Most important to receive at least one hour of deep sleep to be sure brain is detoxed

Curt

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322 - Scientists pinpoint how many hours sleep will increase your risk of heart disease, Independent.co.uk Annie Curtis Thursday 29 May 2025 https://www.independent.co.uk/news/health/sleeping-how-many-hours-heart-health-b2759768.html

A new study has shed light on exactly how a lack of sleep causes harm--

We’ve long known that a lack of sleep is bad for the heart – but scientists are now starting to understand exactly how it causes harm.

In a new study from Uppsala University in Sweden, researchers found that just three nights of restricted sleep – around four hours a night – triggered changes in the blood linked to a higher risk of heart disease.

The researchers looked at inflammatory proteins in the blood. These are molecules the body produces when it is under stress or fighting off illness. When these proteins stay high for a long time, they can damage blood vessels and raise the risk of problems like heart failure, coronary heart disease and atrial fibrillation (irregular heartbeat).

The study involved 16 healthy young men who spent several days in a lab, where everything from their meals to their activity levels and light exposure was carefully controlled.

The participants followed two routines: three nights of normal sleep (8.5 hours) and three night of sleep restriction (4.25 hours). After each sleep phase, the men completed a short, high-intensity cycling workout, and their blood was tested before and after.

Researchers measured almost 90 different proteins in the blood samples. They found that sleep deprivation caused a clear rise in inflammatory markers linked to heart disease. And while exercise usually boosts healthy proteins such as interleukin-6 and BDNF (which support brain and heart health), these responses were weaker after poor sleep.

Strikingly, the changes happened even in young, healthy adults, and after only a few nights of bad sleep. That’s worrying given how common it is for adults to experience poor sleep from time to time – and around one in four people work shifts that disrupt sleep patterns.

The researchers also discovered that the time of day blood was taken mattered: protein levels varied between morning and evening, and even more so when sleep was restricted. This suggests that sleep affects not only what’s in your blood, but when those changes are most visible.
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To Have Regular Hours for Sleep — How prevalent is the habit of turning day into night, and night into day. Many youth sleep soundly in the morning, when they should be up with the early singing birds and be stirring when all nature is awake. CG 111.4

In regulating the hours for sleep, there should be no haphazard work. Students should not form the habit of burning the midnight oil and taking the hours of the day  for sleep. If they have been accustomed to doing this at home, they should correct the habit, going to bed at a seasonable hour. They will then rise in the morning refreshed for the duties of the day. CG 363.3

Diligent study is not the principal cause of the breaking down of the mental powers. The main cause is improper diet, irregular meals, and a lack of physical exercise. Irregular hours for eating and sleeping sap the brain forces. CD 395.1
FAITH - As God's blessed sons & daughters we are to attempt the impossible to the extent that we will fail unless God steps in.   Keep the faith

rahab

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Sleep so important!  Especially deep.

Curt

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334 - Circadian Disruption: The Hidden Cancer Link?
« Reply #84 on: July 24, 2025, 11:51:27 AM »
334 - Circadian Disruption: The Hidden Cancer Link? Medscape Maria Weiss July 16, 2025. https://www.medscape.com/viewarticle/circadian-disruption-hidden-cancer-link-2025a1000ir1?ecd=WNL_trdalrt_pos1_ous_250717_etid7573806&uac=305958HN&impID=7573806

Disruptions to this internal clock, caused by sleep problems, nighttime light exposure, and irregular eating habits, are increasingly linked to the development of cancer.

Since the mid-1970s, the overall cancer incidence has increased, particularly among individuals aged 15-39 years, with an early onset CRC (colorectal cancer) showing the sharpest rise. Over the same period, exposure to artificial light at night (ALAN) has significantly increased. Light emitted from TVs, computer screens, and smartphones can suppress melatonin production, disrupting both sleep and circadian rhythms.

A recent meta-analysis involving more than 170,000 participants found that high ALAN exposure (artificial light at night) increased the risk for estrogen receptor-positive breast cancer in premenopausal women. Similar associations have been reported for thyroid cancer. Crossing time zones may also disrupt circadian rhythms and potentially influence cancer risk.

The gastrointestinal tract is particularly sensitive to circadian disruption. The intestinal mucosa regenerates on a precise 24-hour cycle, and the gut microbiome is highly responsive to rhythm disruption. Dietary intake is also regulated by the circadian clock, and dysregulation may emerge as a significant risk factor for CRC, although further confirmation is needed.

Preserving circadian rhythms may play a significant role in the prevention and treatment of cancer in the future. Strategies include maintaining consistent sleep and mealtimes, limiting night-shift work, and limiting food intake to a 6- to 12-hour window during the day. Regular physical activity may have a positive effect on circadian rhythms.
FAITH - As God's blessed sons & daughters we are to attempt the impossible to the extent that we will fail unless God steps in.   Keep the faith

rahab

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Re: 334 - Circadian Disruption: The Hidden Cancer Link?
« Reply #85 on: July 25, 2025, 02:36:54 PM »
So true

Richard Myers

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Re: 334 - Circadian Disruption: The Hidden Cancer Link?
« Reply #86 on: July 26, 2025, 06:47:34 AM »
Amen!  We know that a virus causes cancer. But, one must ask, why then do so many who eat animal products which often have virus that cause cancer do not come down with cancer?  The human is fearfully and wonderfully made. Our immune system can protect us from the virus developing cancer. We are daily finding out how our immune system works. And, how cancer is able to overcome the immune system. Thus we see that those with a weak immune system are open to virus that cause cancer.  More and more young ones develop cancer because their immune system is weak. Cancer in the past was seen in mainly the elderly. As we get older the immune system weakens and the virus that has been dormant is able to grow and produce tumors. 

What our Brother Curt and others have been sharing reveals how we can strengthen or weaken our immune system. When Covid was first discovered we were told that those with a strong immune system was the best defense against the disease. Yet, this truth was seldom heard again as the number of deaths increased. It would have been very good if those entrusted with the work of healing and preventing disease were to continue to teach what we could do to have a strong immune system. 

God has blessed us with an abundance of light on preventing and curing disease. We pray that we have been faithful in sharing that light. And, we know that the Great Physician is the one who heals the sick and raises the dead. Trusting in His divine power is as important as the natural remedies He has given to us. Then we ought  to strengthen our hold on Jesus that we would trust in Him who gave all that we might live.
Jesus receives His reward when we reflect His character, the fruits of the Spirit......We deny Jesus His reward when we do not.

Curt

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351 - Glymphatics: The Brain's Waste Disposal System During Sleep
« Reply #87 on: October 08, 2025, 05:45:24 AM »
While You Were Sleeping, the Brain’s ‘Waste Disposal System’ Was at Work, Medscape Batya Swift Yasgur, MA, LSW, August 25, 2025 https://www.medscape.com/viewarticle/while-you-were-sleeping-brains-waste-disposal-system-was-2025a1000mbb


The Glymphatic System: Not a Typo, the Brain’s Lymphatic (Waste Disposal) System, MedScape Andrew N. Wilner, MD; Andrew W. Varga, MD, PhD September 09, 2025 https://www.medscape.com/viewarticle/glymphatic-system-not-typo-brains-lymphatic-system-2025a1000nh1?ecd=WNL_trdalrt_pos1_ous_250911_etid7708423&uac=305958HN&impID=7708423


 [CSF or Cerebrospinal fluid is not just a liquid medium in which the brain resides but is being discovered to have much more complex functions. Could this cleaning and removal of waste nightly reduce amyloid plaque between neurons and tau tangles inside brain neurons? - CdG]


 It’s been known for millennia that the human body accumulates waste as a result of day-to-day functioning, but it’s now recognized that the awake, active brain also builds up waste that negatively affects neural function if not removed.


 Thankfully, it was recently discovered that the brain has a garbage removal mechanism.


 “The glymphatic system is a brain-wide network of perivascular spaces that facilitates the clearance of waste products from the brain during sleep,” Jeffrey Iliff, PhD, professor in the Department of Psychiatry and Behavioral Sciences/Department of Neurology, University of Washington School of Medicine, and researcher at the VA Puget Sound, Seattle, told Medscape Medical News.


 This system “serves a similar function in the brain as the lymphatic system does in the rest of the body,” Iliff continued.


The Glymphatic System [Glial cells + Lymphatic fluid]When first described in 2012, there was skepticism that a brain waste clearance system existed in humans but a new proof-of-principle study used contrast MRI imaging to visualize the glymphatic system.


 [Different source, see 2nd link provided above: …. _the finding that really put the glymphatic system on the map, so to speak, was a 2013 paper that described that glymphatic function may be one of sleep’s functions.

 This paper described that, when mammals sleep, all the cells in the brain actually shrink down in size. What that leads to, ultimately, is an expansion of this interstitial space, that now more easily allows clearance of different metabolites right out of the brain parenchyma itself and into the spinal fluid where it can be cleared.]


 He [Jeffery Lliff PhD] has reported that the glymphatic system clears amyloid-beta during sleep. More recent data found it clears tau and alpha-synuclein as well.
 Other suggestions for keeping your glymphatic system healthy are to improve cardiovascular health since the system relies on arterial pulsatility and physical exercise, which has a positive impact on sleep architecture as well as cardiovascular benefits.

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FEARFULLY AND WONDERFULLY MADE
FAITH - As God's blessed sons & daughters we are to attempt the impossible to the extent that we will fail unless God steps in.   Keep the faith

rahab

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Re: 351 - Glymphatics: The Brain's Waste Disposal System During Sleep
« Reply #88 on: October 08, 2025, 05:44:27 PM »
So important!!

Curt

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Re: 351 - Glymphatics: The Brain's Waste Disposal System During Sleep
« Reply #89 on: October 11, 2025, 03:05:02 PM »
another reason for physical activity AND one great reason why the aged among us need to stay active
FAITH - As God's blessed sons & daughters we are to attempt the impossible to the extent that we will fail unless God steps in.   Keep the faith