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287 - A Single Jog Can Improve Glucose Metabolism in Young Adults

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Curt:
MedScape, Edited by Manasi Talwadekar, October 21, 2024

https://www.medscape.com/viewarticle/single-jog-can-improve-glucose-metabolism-young-adults-2024a1000j6f?ecd=WNL_trdalrt_pos1_ous_241023_etid6930111&uac=305958HN&impID=6930111 

TOPLINE:

In healthy young adults, a single 30-minute bout of outdoor aerobic exercise significantly reduces fasting and 1-hour glucose levels during an oral glucose tolerance test (OGTT) the next day and improves insulin sensitivity.

METHODOLOGY:

The researchers investigated the effect of a single bout of aerobic exercise on 1-hour post-load glucose levels during an OGTT in 32 young, healthy, normal-weight or marginally overweight individuals (mean age, 35 years; 14 women and 18 men) with a sedentary or moderately active lifestyle.

The participants underwent an initial OGTT after at least 4 days of physical inactivity, followed by a second OGTT the day after a single 30-minute bout of aerobic exercise.

The exercise session consisted of a light jog for 30 minutes, monitored using a metabolic holter to quantify energy expenditure and exercise intensity. The participants did not undertake any exercise outside the lab sessions.


 TAKEAWAY:-

- A single 30-minute bout of aerobic exercise significantly reduced 1-hour post-load glucose levels from 122.8 mg/dL at baseline to 111.8 mg/dL (P = .03) the day after exercise.

- Post exercise insulin levels also were significantly lower 1 hour after glucose load, decreasing from 57.4 IU/mL at baseline to 43.5 IU/mL the day after exercise (P = .01).

- Insulin sensitivity improved significantly after exercise, along with a reduction in insulin resistance- The study found a trend toward increased beta-cell function the day after an exercise bout, ...


 IN PRACTICE:

"Improvement in 1-hour post-load plasma glucose following a single session of aerobic physical activity suggests that exercise could have a direct effect on T2D [type 2 diabetes] risk and cardiovascular risk," the authors wrote.

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