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289 - Microplastics found in multiple human organ tissues correlated with lesion

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Curt:
289 - Microplastics found in multiple human organ tissues correlated with lesions

PHYS.ORG 30th December 2024, by Justin Jackson
https://phys.org/news/2024-12-microplastics-multiple-human-tissues-lesions.html

Research led by Zhejiang Agriculture and Forestry University in China has performed a metadata investigation into the presence of microplastics in humans. They report a concerning relationship between micro and nano plastic (MNP) concentrations in damaged tissues and links with multiple health conditions.

Consistent methods to pinpoint and quantify MNPs in human tissues are lacking. Reliable data linking MNPs to human diseases are necessary for assessing potential risks and developing mitigation measures.


 In the study, "Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?" published in TrAC Trends in Analytical Chemistry, investigators collected 61 available research articles for MNP detection in human tissues, plus 840 articles on MNP toxicological mechanisms.oxicological studies employed cell models and animal experiments to examine oxidative stress, inflammatory responses, and related signaling pathways.

The studies documented particles detected in skin, arteries, veins, thrombi, bone marrow, testes, semen, uterus, and placenta. MNPs were found in the digestive system, from saliva to feces, liver, and gallstones.Within the respiratory system, MNPs were everywhere, including lung tissue, with microscopic fibers common in bronchoalveolar lavage fluid and sputum.

Positive correlations emerged between particle abundance and specific disorders, such as inflammatory bowel disease, thrombosis, cervical cancer, and uterine fibroids.A critically important signal in the metadata discovered by the researchers was that measured levels of MNPs tended to be higher in tissues with lesions than in non-lesioned tissues. These included inflamed intestines, fibrotic lungs, or cancerous growths, suggesting a potential link between MNP buildup and local pathology.

In the case of "what came first, the lesion or the microplastic," it is possible that MNPs contribute to inflammation, oxidative stress, and cellular damage, which can cause or worsen tissue lesions. But it is also possible that these lesions accumulate more MNPs in already damaged tissue areas. While the current findings do not provide a direct cause-and-effect relationship, they offer good targets for further study.

There are no conventional methods for removing microplastics from the environment or human tissues.

rahab:
Very bad

How are we getting these into our bodies?

Curt:
very good question. The key is in the word, "micro" from "microscopic" or things that one cannot see with the naked eye.
Microplastics can be from contaminated water sources and foods like meat products where animals and sea creatures ingest it from their environment, water cources like rivers and seas.

Think of Sperm whales for example that open their mouth wide and scoop plankton constantly. It is very easy for them to ingest small plastics and microplastics in the ocean. It is an extreme to make the point.

rahab:
There must be a way to get rid of them. 

Bromeliad ?

Nattokinase?

Turmeric?

Leafy greens?

Curt:
At this point we just do not know enough about microplastics.

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