There were no supplements in the Garden of Eden, but also no sin.
It seems practical to consider a tiered approach -- (1) the application of natural principles, such as diet, exercise, sun exposure and so on, (2) nutritional supplements if necessary, and (3) more heroic measures. An example of the last of these would be getting into a car accident, and being rushed to the ER, where all the latest drugs and technologies are applied to save one's life.
It's interesting to note the experience of Ellen White and Dr. Kress. She was given a vision, in which she observed the deathly pallor of his hands (5BIO 119). He was suffering from pernicious anemia, and she advised him to use raw or cooked eggs to get vitamin B-12 (12MR 168).
This is not necessarily a case of "Go thou and do likewise", but it's a useful data point for some people in some situations.